The collapse of financial markets during the past week capped a year long slide that saw a loss of $8.4 trillion during the past year, $2.4 trillion of which came last week, as measured by the Dow Jones Wilshire 5000, the Associated Press reported. The meltdown reflected a global capital crisis. Though investors seem to be hunting for a bottom, volatility is expected to continue as wild swings in the market and concerns that it will be a deep recession and a long bear market ahead. Biotech has fared better than the general market and may be buoyed by the fact that people get sick in good markets as well as bad, but a large part of the sector, which is now sitting with market caps below $100 million, will have a challenging time raising capital needed to carry their pipelines through the clinic and into the market.